Thermo Fisher Scientific NFYB Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1:50-1:100

-

ChIP assay (ChIP)

5-10 µg

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Raised against recombinant NF-YB protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Frozen

Concentration

Lot-Specific

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Dry ice

Target Information

The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein, histone-fold handshake motif in a manner analogous to the histone proteins H2B and H2A, respectively.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.