Thermo Fisher Scientific NFYB Polyclonal Antibody

Applications 및 Tested Dilution

Product Specifications

Target Information

The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is composed of three subunits: NF-YA, NF-YB, and NF-YC. All three components are necessary for DNA binding. Each NF-Y subunit contains a conserved region required for formation of the NF-Y–DNA complex, which is homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of NF-YB and NF-YC are suggested to interact via a histone-fold “handshake” motif, similar to histone proteins H2B and H2A, respectively.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.