Thermo Fisher Scientific NFYB Polyclonal Antibody
NFYB 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. ICC/IF 및 ChIP assay에 적합하며, 동결 상태로 제공. NF-Y 복합체 연구에 활용 가능. 연구용으로만 사용.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ChIP assay (ChIP) | 5–10 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Raised against recombinant NF-YB protein |
| Conjugate | Unconjugated |
| Form | Frozen |
| Concentration | Lot-Specific |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Dry ice |
Target Information
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is composed of three subunits: NF-YA, NF-YB, and NF-YC. All three components are necessary for DNA binding. Each NF-Y subunit contains a conserved region required for formation of the NF-Y–DNA complex, which is homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of NF-YB and NF-YC are suggested to interact via a histone-fold “handshake” motif, similar to histone proteins H2B and H2A, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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