Thermo Fisher Scientific HDAC1 Polyclonal Antibody
HDAC1 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, ICC/IF, ELISA, ChIP, ChIP-Seq 등 다양한 응용에 사용 가능. 인간 유래 항원으로 제작되었으며 고농도 액상 형태로 제공. 연구용으로만 사용.
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Thermo Fisher Scientific HDAC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunocytochemistry (ICC/IF) | 1:500 | - |
| ELISA | 1:4,000 | - |
| ChIP assay (ChIP) | 2.5 µg/10^6 cells | View 1 publication |
| ChIP-sequencing (ChIP-Seq) | 2 µg/4x10^6 cells | - |
Product Specifications
| Property | Description |
|---|---|
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Raised in rabbits against the C-terminal region of human HDAC1, using a KLH-conjugated synthetic peptide. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.73 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
| RRID | AB_2533875 |
Target Information
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression.
HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex.
It interacts with retinoblastoma tumor-suppressor protein, contributing to the control of cell proliferation and differentiation.
Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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