Thermo Fisher Scientific DNMT3B Polyclonal Antibody
DNMT3B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. ELISA, IP, ChIP, RIP 등 다양한 애플리케이션에 사용 가능. 액상 형태로 제공되며 -20°C에서 보관. 마우스 DNMT3B 단백질에 대해 생성된 항체로 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| ELISA (ELISA) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
| ChIP assay (ChIP) | 0.2 µg |
| RNA Immunoprecipitation (RIP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Raised against the mouse DNMT3B protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-Specific |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
| RRID | AB_2533878 |
Target Information
CpG methylation is an epigenetic modification important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development.
This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated.
Mutations in this gene cause immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described, though the full-length sequences of variants 4 and 5 have not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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