Thermo Fisher Scientific S1P1 Monoclonal Antibody (1E3H5)
S1P1 단백질을 표적으로 하는 Mouse Monoclonal Antibody (Clone 1E3H5). Western blot, IHC, ICC/IF, Flow Cytometry, ELISA 등 다양한 응용에 적합. Human 시료 반응성. Protein G 정제, PBS buffer, 4°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E3H5 |
| Immunogen | Purified recombinant fragment of human CD363 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091061 |
Target Information
S1P1 (Sphingosine-1-phosphate receptor 1) is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P), coupled to the G(i) subclass of heteromeric G proteins. S1P1 signaling activates RAC1, SRC, PTK2/FAK1, and MAP kinases, playing a crucial role in cell migration through actin cytoskeleton reorganization and lamellipodia formation. It is essential for normal chemotaxis toward S1P, embryonic heart development, and cardiac morphogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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