Thermo Fisher Scientific ESRRA Monoclonal Antibody (6F1E6)
ESRRA 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC, ICC/IF, Flow Cytometry, ELISA 등 다양한 응용에 적합합니다. Human 및 Rat 시료에 반응하며, Protein G로 정제된 1 mg/mL 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6F1E6 |
| Immunogen | Purified recombinant fragment of human ESRRA (AA: 198–376) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093312 |
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan member of the nuclear hormone receptor superfamily. ERR family members share an almost identical DNA-binding domain with 68% amino acid identity to that of the estrogen receptor. ERRα binds to an ERR response element (ERRE) containing a single consensus half-site (5'-tnaaggtca-3') and can interact with the medium-chain acyl-CoA dehydrogenase (MCAD) response element NRRE-1, acting as a key regulator of MCAD promoter activity. ERR1 functions as a metabolic regulator and is expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for ERR1 is NR3B1.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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