Thermo Fisher Scientific ARHGAP24 Polyclonal Antibody
ARHGAP24 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트에서 반응하며 WB, IHC, ICC, ELISA 등 다양한 응용 가능. Protein A로 정제된 액상 항체로 -20°C 보관. 세포극성 및 형태 연구용.
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Thermo Fisher Scientific ARHGAP24 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ARHGAP24 (amino acids 501–600) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Rho GTPase-activating protein involved in cell polarity, morphology, and cytoskeletal organization. Acts as a GTPase activator for Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho, leading to suppression of leading-edge protrusion and promotion of cell retraction for polarity. Suppresses RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding and disruption of actin stress fibers, forming membrane ruffles, lamellipodia, and filopodia. Isoform 2 is vascular cell-specific and modulates angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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