Thermo Fisher Scientific PROK2 Polyclonal Antibody
PROK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. 고순도 Protein A 정제, 1 mg/mL 농도, -20°C 보관. 인간, 마우스, 랫트 반응성.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human PROK2 (Prokineticin 2), amino acids 28–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Prokineticin-2 (PK2) is a cysteine-rich secreted protein expressed in the suprachiasmatic nucleus (SCN), with receptors located in key autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is regulated by the circadian clock and modulated by light, functioning as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression peaks during the day and responds to nocturnal light pulses. Additionally, PK2 acts as a chemoattractant for neuronal progenitors derived from the subventricular zone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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