Thermo Fisher Scientific RAD52 Recombinant Rabbit Monoclonal Antibody (ARC1183)
RAD52 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 RAD52에 특이적으로 반응하며 HEK293 세포에서 발현되었습니다. 고순도의 액상 항체로, PBS 버퍼에 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1183 |
| Immunogen | Synthetic peptide corresponding to amino acids 319–418 of human RAD52 (UniProt ID: P43351) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849571 |
Product Specific Information
Immunogen sequence:
QELIKTLEDN SEKWAVTPDA GDGVVKPSSR ADPAQTSDTL ALNNQMVTQN RTPHSVCHQK PQAKSGSWDL QTYSADQRTT GNWESHRKSQ DMKKRKYDPS
Target Information
DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. These breaks are repaired via two main pathways: homologous recombination (HR) or non-homologous end joining (NHEJ).
Homologous recombination involves members of the RAD52 epistasis group, including RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2.
RAD52 catalyzes strand annealing reactions and forms oligomers that attach to single-stranded DNA ends.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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