Thermo Fisher Scientific RAD52 Recombinant Rabbit Monoclonal Antibody (ARC1183)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1183

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 319-418 of human Rad52 (P43351) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAD52,uniProtId:P43351-1,ncbiNodeId:9606,antigenRange:319-418,antigenLength:418,antigenImageFileName:MA5-35671_RAD52_P43351-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35671_RAD52_P43351-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849571

Product Specific Information

Immunogen sequence: QELIKTLEDN SEKWAVTPDA GDGVVKPSSR ADPAQTSDTL ALNNQMVTQN RTPHSVCHQK PQAKSGSWDL QTYSADQRTT GNWESHRKSQ DMKKRKYDPS

Target Information

DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which includeRAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.