Thermo Fisher Scientific Cactin Polyclonal Antibody
Cactin 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. Western Blot 및 Immunoprecipitation에 사용 가능하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C에서 보관, 연구용으로 적합합니다.
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Thermo Fisher Scientific Cactin Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 475 and 525 of human Cactin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidence shows that overexpression of Cactin suppresses TLR-induced activation of NF-κB and interferon-regulatory factor transcription factors, and induction of TLR-responsive genes. It is also reported that Cactin interacts with IkB-like protein and targets other proteins encoded by genes in the MHC Class III region of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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