Thermo Fisher Scientific Cactin Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 Cactin 단백질(75-125번 잔기 영역)에 특이적 결합. Western blot 및 Immunoprecipitation에 적합. 액상 형태, 1 mg/mL 농도. 4°C 보관, 연구용 전용.
- 카탈로그번호
- A303349Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Cactin Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 75 and 125 of human Cactin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidence shows that overexpression of Cactin suppresses TLR-induced activation of NF-κB and interferon-regulatory factor transcription factors, as well as induction of TLR-responsive genes. It is also reported that Cactin interacts with IκB-like protein and targets other proteins encoded by genes in the MHC Class III region of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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