Thermo Fisher Scientific Cactin Polyclonal Antibody
Human Cactin 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 75 and 125 of human Cactin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Cactin is a novel negative regulator of TLR signaling and functions by targeting MHC Class III genes at the molecular and functional levels. It is localized in the nucleus, which is essential for its inhibitory role in TLR signaling. Overexpression of Cactin suppresses TLR-induced activation of NF-κB and interferon-regulatory factor transcription factors, reducing expression of TLR-responsive genes. Additionally, Cactin interacts with IkB-like protein and other proteins encoded by genes in the MHC Class III region of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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