Thermo Fisher Scientific SIPA1L3 Polyclonal Antibody
SIPA1L3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 사용 가능. Human 시료 반응성, 항원 친화 크로마토그래피 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications
- Western Blot (WB): 1:1,000–1:5,000
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of Human Signal-Induced Proliferation-Associated 1 Like 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Signal-induced proliferation associated-like protein 3 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 is a molecular component of tight junctions and adherens junctions, suggesting a role in balancing Rap1 activity by counteracting RapGEFs.
Studies indicate deregulation of SIPA can lead to myeloproliferative stem cell disorders in mice and increased metastasis in human cancers. SIPA1L1 may also play roles in embryonic development and cell proliferation. Due to sequence homology, SIPA1L3 may have similar functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: A304-155A-T_SIPA1L3_O60292-1_Rabbit.svg, A304-155A-T_SIPA1L3_O60292-1_Rabbit_PDP.jpeg)
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