Thermo Fisher Scientific MMP13 Monoclonal Antibody (OTI2A6), TrueMAB
Human MMP13 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC(P), ICC/IF에 사용 가능. 고순도 Affinity chromatography 정제, Lyophilized 형태로 제공. 연구용으로 적합하며 재구성 및 conjugation 실험에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MMP13 Monoclonal Antibody (OTI2A6), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A6 |
| Immunogen | Human recombinant protein fragment (aa 104–471 of human MMP13, produced in HEK293T cell) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MMP13 (collagenase 3) participates in the degradation of extracellular matrix proteins, including fibrillar collagen, fibronectin, tenascin-C (TNC), and aggrecan (ACAN).
It cleaves triple-helical collagens (types I, II, III), with the highest activity toward soluble type II collagen.
MMP13 also degrades collagen types IV, XIV, and X, and plays roles in wound healing, tissue remodeling, cartilage degradation, bone development, mineralization, and ossification.
It is essential for normal embryonic bone development and ossification.
Mutations in MMP13 are associated with spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.