Thermo Fisher Scientific PMS1 Monoclonal Antibody (OTI5E10), TrueMAB
Human PMS1 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 최적화됨. E.coli에서 생산된 PMS1(aa 323-423) 재조합 단백질을 면역원으로 사용. 동결건조 형태로 제공되며 PBS, trehalose buffer에 저장. 연구용으로 DNA mismatch repair 관련 연구에 적합.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 323–423 of human PMS1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The PMS1 gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family.
This protein participates in DNA mismatch repair and forms heterodimers with MLH1, another repair protein.
Mutations in PMS1 are associated with hereditary nonpolyposis colorectal cancer type 3 (HNPCC3), also known as Lynch syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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