Thermo Fisher Scientific CDH10 Polyclonal Antibody
Human CDH10 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. 고순도 Affinity chromatography 정제 방식으로 제조되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 뇌 조직 내 CDH10 연구에 적합합니다.
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Thermo Fisher Scientific CDH10 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:3,000
Publications: [참고 문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CDH10 (Accession Q9Y6N8), corresponding to amino acid residues G754–S788 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852413 |
Product Specific Information
Antibody detects endogenous levels of total CDH10.
Target Information
CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain.
The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein’s homophilic cell adhesion activity.
Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.
This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth, and guidance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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