Thermo Fisher Scientific SEPP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Non-human primate, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human SELENOP(Accession P49908), corresponding to amino acid residues A239-R261. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SEPP1,uniProtId:P49908-1,ncbiNodeId:9606,antigenRange:239-261,antigenLength:381,antigenImageFileName:PA5-103044_SEPP1_P49908-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103044_SEPP1_P49908-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2852414

Product Specific Information

Antibody detects endogenous levels of total SEPP1.

Target Information

A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorder, control of the aging and neurodiseases process. Selenoproteins are thought to be responsible for the majority of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified until now. Although the function of many selenoproteins are unknown, some play important roles in anti-oxidant mechanisms. It has been also implicated in the regulation of signaling pathways through catalysis of thiol/disulfide exchange. Selenoprotein M (SelM) is especially expressed in a mammalian brain and is localized to the perinuclear structures (Golgi/ER). The roles of selM have not been clearly identified until present time.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.