Thermo Fisher Scientific Cathepsin B Recombinant Rabbit Monoclonal Antibody (JA11-02)
Recombinant rabbit monoclonal antibody for Cathepsin B detection. Validated in WB, IHC(P), and ICC/IF. High specificity and consistency with Protein A purification. Supplied in TBS buffer with glycerol and BSA. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JA11-02 |
| Immunogen | Recombinant protein within Human Cathepsin B (aa 7–176) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809928 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed, followed by screening to select optimal clones for production.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
Cathepsin B is a lysosomal cysteine protease implicated in the pathogenesis of rheumatoid arthritis, muscular dystrophy, and tumor metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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