
Thermo Fisher Scientific LSM11 Monoclonal Antibody (OTI1H1), TrueMAB
LSM11 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, 무보존제 동결건조 형태로 제공됩니다. 재구성 후 약 1 mg/mL 농도로 사용 가능하며, 연구용으로 적합합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H1 |
| Immunogen | Full length human recombinant protein of human LSM11 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
LSm11 is a 360-amino-acid nuclear protein belonging to the LSm subfamily of snRNP Sm proteins. It contains an N-terminal domain required for pre-mRNA cleavage and binds specifically to U7 snRNA, playing a role in cell cycle regulation and cell growth.
The human LSM11 gene is located on chromosome 5, which spans approximately 181 million base pairs and represents about 6% of the human genome. Deletions in chromosome 5 are associated with Cri du chat syndrome and certain therapy-related leukemias and myelodysplastic syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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