Thermo Fisher Scientific FZD8 Polyclonal Antibody
FZD8 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 8–20 µg/mL 농도로 사용됩니다. Human, Mouse 등 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS에 0.1% sodium azide가 포함된 액상 형태로 제공됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific FZD8 Polyclonal Antibody
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 8–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Mouse, Non-human primate, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd extracellular domain of human FZD8 / Frizzled 8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550942 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Dog, Rabbit, Opossum (100%)
Lizard (94%), Monkey (81%)
Target Information
Members of the Frizzled family encode seven-transmembrane domain proteins that act as receptors for the Wingless type MMTV integration site family of signaling proteins.
Most Frizzled receptors are coupled to the beta-catenin canonical signaling pathway.
Frizzled 8 is highly expressed in two human cancer cell lines, suggesting a potential role in various cancers.
Expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle.
ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries.
The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.