Thermo Fisher Scientific FZD8 Polyclonal Antibody
FZD8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC(P)에서 30 µg/mL로 검증됨. 인간, 마우스, 원숭이, 랫트 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 보관.
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Thermo Fisher Scientific FZD8 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 30 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from N-terminal extracellular domain of human FZD8 / Frizzled 8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550941 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Monkey, Marmoset, Mouse, Rat, Panda, Opossum (100%).
Target Information
Members of the Frizzled family encode seven-transmembrane domain proteins that serve as receptors for the Wingless-type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway.
Frizzled 8 is highly expressed in two human cancer cell lines, suggesting a potential role in various cancer types. Expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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