Thermo Fisher Scientific IL6R Monoclonal Antibody (OTI1B5), TrueMAB
Human IL6R 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1B5). Western blot에 최적화된 TrueMAB 형식의 항체로, 고순도 친화 크로마토그래피 정제. PBS/BSA/glycerol buffer에 보관되며 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B5 |
| Immunogen | Full length human recombinant protein of IL6R produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor.
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. IL6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays a key role in immune response.
The IL6 receptor complex consists of IL6R and the interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), which is shared by several other cytokines.
Dysregulated IL6/IL6R expression is associated with diseases such as multiple myeloma, autoimmune disorders, and prostate cancer.
Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene exists on chromosome 9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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