Thermo Fisher Scientific AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Monoclonal Antibody (MBS-12)
인간 AFP를 인식하는 Mouse IgG1 단클론 항체로, 간세포암 및 생식세포종양 마커 연구에 적합. IHC, ICC, Flow Cytometry 등 다양한 응용 가능. 고순도 Protein A/G 정제, 보존제 무첨가 PBS 용액 형태.
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Thermo Fisher Scientific AFP (Alpha Fetoprotein) Monoclonal Antibody (MBS-12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 0.5–1 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MBS-12 |
| Immunogen | Human Alpha Fetoprotein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract, and liver during fetal development. In adults, AFP expression is often associated with hepatoma or teratoma, though hereditary persistence may occur without pathology. AFP is considered the fetal counterpart of serum albumin, with both genes located in tandem on chromosome 4. It exists in monomeric, dimeric, and trimeric forms and can bind copper, nickel ions, fatty acids, and bilirubin. AFP levels in amniotic fluid are used to assess renal protein loss and screen for spina bifida and anencephaly. Elevated serum AFP is observed in hepatocellular carcinoma, teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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