Thermo Fisher Scientific MEI1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MEI1 protein for immunohistochemistry use. Recombinant protein immunogen, antigen affinity purified, supplied in PBS with glycerol and sodium azide. Suitable for research on meiosis and male infertility mechan...
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MEI1 (Product #RP-95369) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2643864 |
Product Specific Information
- Immunogen sequence:
HMKEKFSKKL ASSSFIRLTL ELKARFCSGL SHSALNQVCS NFLYYMCLNL LSAPEKTGPP SKEELSAVSE LLQHGLPQIS SRS - Highest antigen sequence identity to orthologs:
- Mouse: 86%
- Rat: 81%
Target Information
MEI1 (Meiosis inhibitor protein 1), also known as Meiosis defective protein 1, is a 1274 amino acid protein crucial for the formation of genetically programmed double-strand breaks, initiating meiosis. Predominantly expressed in testis, MEI1 gene defects may lead to male infertility due to meiotic arrest. Genetic variations in MEI1 are associated with infertility in certain populations. Human MEI1 shares 79% sequence similarity with its mouse homolog and has seven isoforms resulting from alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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