Thermo Fisher Scientific LYPD6B Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LYPD6B if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LYPD6B,uniProtId:Q8NI32-1,ncbiNodeId:9606,antigenRange:36-175,antigenLength:183,antigenImageFileName:PA5-61915_LYPD6B_Q8NI32-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61915_LYPD6B_Q8NI32-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643629

Product Specific Information

Immunogen sequence: WAFAKNINFY NVRPPLDPTP FPNSFKCFTC ENAGDNYNCN RWAEDKWCPQ NTQYCLTVHH FTSHGRSTSI TKKCASRSEC HFVGCHHSRD SEHTECRSCC EGMICNVELP TNHTNAVFAV MHAQRTSGSS APTLYLPVLA

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Target Information

Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.