Thermo Fisher Scientific COX18 Polyclonal Antibody

Thermo Fisher Scientific COX18 Polyclonal Antibody

Applications

• Immunohistochemistry (Paraffin) (IHC (P))

Tested Dilution: 1:10–1:50
Publications: -

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total COX18 protein.

Target Information

COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain.
It is required for the insertion of integral membrane proteins into the mitochondrial inner membrane and is essential for the activity and assembly of cytochrome c oxidase.
COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.