Thermo Fisher Scientific CMTM1 Polyclonal Antibody
CMTM1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인체 시료에 반응합니다. IHC(P)에서 1:10~1:100 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 0.3 mg/mL 농도의 액상 형태로 -20°C에서 보관합니다.
- 카탈로그번호
- PA550491
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:10–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal of human CKLF-like MARVEL transmembrane domain-containing protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635944 |
Product Specific Information
This antibody detects endogenous levels of total CKLF1 / CMTM1 protein.
Target Information
Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine-like factor superfamily (CKLFSF) share similarities with both chemokine and transmembrane 4 superfamilies of signaling molecules.
As a member of the CKLFSF family, CMTM1 (CKLF-like MARVEL transmembrane domain-containing protein 1), also known as CKLFSF1, is a 169 amino acid multi-pass membrane protein highly expressed in testis, likely involved in spermatogenesis or testicular development.
CMTM1 contains a CC-chemokine motif and four transmembrane segments. The gene encoding CMTM1 resides in a tight gene cluster on human chromosome 16 with CKLF, CMTM2, CMTM3, and CMTM4. There are at least sixteen isoforms of CMTM1 resulting from alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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