Thermo Fisher Scientific CMTM1 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:10–1:100

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total CKLF1 / CMTM1 protein.

Target Information

Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine-like factor superfamily (CKLFSF) share similarities with both chemokine and transmembrane 4 superfamilies of signaling molecules.
As a member of the CKLFSF family, CMTM1 (CKLF-like MARVEL transmembrane domain-containing protein 1), also known as CKLFSF1, is a 169 amino acid multi-pass membrane protein highly expressed in testis, likely involved in spermatogenesis or testicular development.
CMTM1 contains a CC-chemokine motif and four transmembrane segments. The gene encoding CMTM1 resides in a tight gene cluster on human chromosome 16 with CKLF, CMTM2, CMTM3, and CMTM4. There are at least sixteen isoforms of CMTM1 resulting from alternative splicing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.