Thermo Fisher Scientific CD23 (Fc Epsilon RII) Monoclonal Antibody (FCER2/3592)
인간 CD23(Fc Epsilon RII)을 인식하는 마우스 단클론 항체로, IHC 및 Peptide Array에 적합합니다. 단백질 A/G로 정제된 액상 형태이며, 4°C에서 보관합니다. 비결합형 항체로 다양한 형식(바이오틴 등)으로 제공됩니다.
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Thermo Fisher Scientific CD23 (Fc Epsilon RII) Monoclonal Antibody (FCER2/3592)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FCER2/3592 |
| Immunogen | Recombinant fragment (around aa 48–321) of human FCER2/CD23 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
CD23 is a 45 kDa glycoprotein expressed on a subset of peripheral blood and tonsil B cells, and strongly expressed on EBV-transformed B lymphoblasts. It is identical to the low-affinity IgE receptor found on B cells. Expression has been observed in neoplastic cells from B cell chronic lymphocytic leukemia and certain lymphoma cases. Functionally, CD23 participates in B cell growth, differentiation, and IgE production. Its soluble form acts as a potent mitogenic factor. CD23 dysfunction is associated with chronic conjunctivitis and chronic lymphocytic leukemia.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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