Thermo Fisher Scientific CD23 (Fc Epsilon RII) Monoclonal Antibody (FCER2/3592)
인간 CD23(Fc Epsilon RII)을 표적하는 단일클론 항체로, IHC(P), IHC(PFA), Peptide Array 등에 사용 가능. 마우스 IgG2b, kappa 형식이며, 1 mg/mL 농도의 액상 제품. B 세포 성장, 분화 및 IgE 생산 연구에 적합.
- 카탈로그번호
- 2208-MSM2-P1ABX
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FCER2/3592 |
| Immunogen | Recombinant fragment (around aa 48–321) of human FCER2/CD23 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
CD23 is a 45 kDa glycoprotein present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. It is identical to the low-affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases of centroblastic/centrocytic lymphoma.
Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. CD23 also has a soluble form that acts as a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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