Thermo Fisher Scientific CD23 (Fc Epsilon RII) Monoclonal Antibody (FCER2/4918)
CD23(Fc Epsilon RII) 단일클론 항체로 인간 시료에 반응하며, IHC(P) 및 IHC(PFA) 실험에 사용 가능. FCER2/4918 클론 기반으로 제작된 비결합형 액상 항체로, B세포 성장 및 IgE 관련 연구에 적합. 냉동(-20°C) 보관 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FCER2/4918 |
| Immunogen | Recombinant fragment (around aa 48–321) of human FCER2/CD23 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD23 is a 45 kDa glycoprotein present on a subpopulation of freshly isolated peripheral blood and tonsil B cells, and strongly expressed on EBV-transformed B lymphoblasts.
The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression has been detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some centroblastic/centrocytic lymphoma.
Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. It also has a soluble form acting as a potent mitogenic factor.
Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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