Thermo Fisher Scientific CD19 Monoclonal Antibody (OTI3B10)
CD19 단백질을 표적하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관 가능. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B10 |
| Immunogen | Full length human recombinant protein of human CD19 (NP_001761) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Available Conjugate Formats
- DyLight 488 (TA506236DM)
- PE (TA506236HM)
- Custom conjugation available (Request form)
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells and can also appear on certain myeloid leukemia cells. CD19 serves as a key regulator of B cell proliferation and differentiation, functioning as a signal-amplifying coreceptor for the B cell receptor (BCR). It plays a central role in multiple signaling pathways related to immune response regulation. Mutations in CD19 can lead to hypogammaglobulinemia, while overexpression may cause B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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