Thermo Fisher Scientific ANAPC11 Monoclonal Antibody (OTI1A8), TrueMAB
인간 ANAPC11 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC, ICC/IF에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태, -20°C 보관. 세포 주기 관련 APC/C 복합체 연구용으로 적합.
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Thermo Fisher Scientific ANAPC11 Monoclonal Antibody (OTI1A8), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A8 |
| Immunogen | Full length human recombinant protein of human ANAPC11 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Together with the cullin protein ANAPC2, ANAPC11 constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.
The APC/C complex mediates ubiquitination and subsequent degradation of target proteins, primarily forming Lys-11-linked polyubiquitin chains and, to a lesser extent, Lys-48- and Lys-63-linked chains.
ANAPC11 may recruit E2 ubiquitin-conjugating enzymes to the complex. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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