Thermo Fisher Scientific Ksp-Cadherin (Kidney-Specific Cadherin)/CDH16 Monoclonal Antibody (SPM594)
Kidney-specific cadherin(CDH16)을 인식하는 단클론 항체로, Western blot과 면역조직화학(IHC)에 적합. 다양한 종(Dog, Human, Mouse, Rabbit, Rat)에 반응하며, Protein A/G 정제. 액상 형태로 4°C 보관, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM594 |
| Immunogen | Recombinant full-length human CDH16 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cadherins are a family of Ca²⁺-dependent adhesion molecules that mediate cell-cell binding, essential for maintaining tissue structure and morphogenesis.
Cadherin-16 (Ksp-Cadherin) is a type I membrane protein expressed specifically in the kidney, localized to the basolateral membrane of renal tubular epithelial cells.
The human Ksp-cadherin gene (CDH16) maps to chromosome 16q21–q22, while the mouse homolog is located on distal chromosome 8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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