Thermo Fisher Scientific RAB5A Polyclonal Antibody
RAB5A 단백질을 인식하는 Sheep 폴리클로날 항체로, Mouse와 Rat 시료에서 반응합니다. Western blot 및 IHC에 사용 가능하며, 동결건조 형태로 제공됩니다. 세포 내 소포 이동 및 막 융합 연구에 적합한 연구용 항체입니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RAB5A Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
- Publications: View 2 publications
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
- Publications: View 2 publications
Miscellaneous PubMed (Misc)
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the internal region of mouse Ras-related protein Rab-5A (RAB5A) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat.
- Specificity of this antibody: RAB5A
Target Information
RAB5 belongs to the small GTPase Rab family, key regulators of intracellular membrane trafficking—from vesicle formation to membrane fusion.
Rabs cycle between inactive GDP-bound and active GTP-bound forms, recruiting downstream effectors responsible for vesicle formation, movement, tethering, and fusion.
RAB5A is required for fusion of plasma membranes and early endosomes, contributes to filopodia extension, and regulates exosomal release of SDCBP, CD63, PDCD6IP, and syndecan.
It also regulates maturation of apoptotic cell-containing phagosomes, likely downstream of DYN2 and PIK3C3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.