Thermo Fisher Scientific IRF1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5 µg/mL

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

1:200

-

ChIP assay (ChIP)

Assay-dependent

-

Product Specifications

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human IRF1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IRF1,uniProtId:P10914-1,ncbiNodeId:9606,antigenRange:104-181,antigenLength:325,antigenImageFileName:PA5-64093_IRF1_P10914-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64093_IRF1_P10914-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642775

Product Specific Information

Immunogen sequence: SAVRVYRMLP PLTKNQRKER KSKSSRDAKS KAKRKSCGDS SPDTFSDGLS SSTLPDDHSS YTVPGYMQDL EVEQALTP

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.

Target Information

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppression. Diseases associated with IRF1 include gastric cancer, somatic and lung cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.