Thermo Fisher Scientific KV4.3 (KCND3) Polyclonal Antibody
Rabbit polyclonal antibody against human KV4.3 (KCND3) for IHC (Paraffin). Recognizes recombinant KCND3 protein. High sequence identity with mouse and rat orthologs. Supplied as liquid, 0.2 mg/mL, in PBS with 40% glycerol and 0.02% sodium azide. For re...
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Applications
Tested Applications and Dilutions
| Application | Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KCND3. Recombinant protein control fragment (Product # RP-91276) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642917 |
Product Specific Information
Immunogen sequence:
NYPSTRSPSL SSHPGLTTTC CSRRSKKTTH LPNSNLPATR LRSMQELSTI HIQGSEQPSL TTSRSSLNLK ADDGLRPNCK TSQITTAIIS IPTPPALTPE GESRPPPASP GPNTNIPSIA SNVVKVS
Highest antigen sequence identity to orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
Voltage-gated potassium (Kv) channels are complex ion channels with diverse physiological roles, including regulation of neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
Four sequence-related potassium channel genes—shaker, shaw, shab, and shal—have been identified in Drosophila, each with human homologs.
The KCND3 gene encodes a member of the voltage-gated, shal-related potassium channel subfamily, forming A-type potassium ion channels important in the repolarization phase of the action potential.
This gene produces two isoforms via alternatively spliced transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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