Thermo Fisher Scientific SMC4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SMC4. Recombinant protein control fragment (Product #RP-92412). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SMC4,uniProtId:Q9NTJ3-1,ncbiNodeId:9606,antigenRange:564-693,antigenLength:1288,antigenImageFileName:PA5-56150_SMC4_Q9NTJ3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56150_SMC4_Q9NTJ3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647619

Product Specific Information

Immunogen sequence: KLTQEETNFK SLVHDLFQKV EEAKSSLAMN RSRGKVLDAI IQEKKSGRIP GIYGRLGDLG AIDEKYDVAI SSCCHALDYI VVDSIDIAQE CVNFLKRQNI GVATFIGLDK MAVWAKKMTE IQTPENTPRL

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Target Information

The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.