Thermo Fisher Scientific SMC4 Polyclonal Antibody
SMC4 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF에 적합합니다. Human, Mouse, Rat에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 고품질의 특이성과 재현성을 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SMC4. Recombinant protein control fragment (Product #RP-92412) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647619 |
Product Specific Information
Immunogen sequence:
KLTQEETNFK SLVHDLFQKV EEAKSSLAMN RSRGKVLDAI IQEKKSGRIP GIYGRLGDLG AIDEKYDVAI SSCCHALDYI VVDSIDIAQE CVNFLKRQNI GVATFIGLDK MAVWAKKMTE IQTPENTPRL
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 92%
Target Information
The proteins belonging to the structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins form two distinct heterodimeric complexes in the cell:
- hCAP-C/hCAP-E (human chromosome-associated protein complex)
- hSMC1/hSMC3 complex
These complexes are essential for maintaining chromosome structure and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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