Thermo Fisher Scientific Prostaglandin E Receptor EP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 300-400 of human PGE receptor EP1 (PGE receptor EP1 (PTGER1)) (NP_0009462) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Prostaglandin E Receptor EP1,uniProtId:P34995-1,ncbiNodeId:9606,antigenRange:300-400,antigenLength:402,antigenImageFileName:PA5-88476_Prostaglandin_E_Receptor_EP1_P34995-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88476_Prostaglandin_E_Receptor_EP1_P34995-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804938

Product Specific Information

Immunogen sequence: VGIMVVSCIC WSPMLVLVAL AVGGWSSTSL QRPLFLAVRL ASWNQILDPW VYILLRQAVL RQLLRLLPPR AGAKGGPAGL GLTPSAWEAS SLRSSRHSGL S; Positive Samples: Mouse pancreas; Cellular Location: Cell membrane, Multi-pass membrane protein

Target Information

The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor`s activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.