Thermo Fisher Scientific SELENBP1 Polyclonal Antibody
SELENBP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 243–472 of human SELENBP1 (NP_0039352) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.96 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804907 |
Product Specific Information
Immunogen sequence:
SLKDGLIPLE IRFLHNPDAA QGFVGCALSS TIQRFYKNEG GTWSVEKVIQ VPPKKVKGWL LPEMPGLITD ILLSLDDRFL YFSNWLHGDL RQYDISDPQR PRLTGQLFLG GSIVKGGPVQ VLEDEELKSQ PEPLVVKGKR VAGGPQMIQL SLDGKRLYIT TSLYSAWDKQ FYPDLIREGS VMLQVDVDTV KGGLKLNPNF LVDFGKEPLG PALAHELRYP GGDCSSDIWI
Positive Samples: MCF7, Mouse liver, Mouse kidney
Cellular Location: Cytoplasm, Membrane, Nucleus, Peripheral membrane protein, Cytosol
Target Information
Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cancer, and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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