Thermo Fisher Scientific NCKAP1 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
MSRSVLQPSQ QKLAEKLTIL NDRGVGMLTR LYNIKKACGD PKAKPSYLID KNLESAVKFI VRKFPAVETR NNNQQLAQLQ KEKSEILKNL ALYYFTFVDV MEFKDHVCEL LNTIDVCQVF FDITVNFDLT KNYLDLIITY TTLMILLSRI EERKAIIGLY NYAHEMTHGA SDREYPRLGQ MIVDYENPLK KMMEEFVPHS KSLSDALISL QMVYPRRNLS ADQWRNAQLL SLISAPSTML NPAQSDTMPC

Positive Samples:
U-87MG, HeLa, MCF7, HepG2, Mouse heart, Rat brain

Cellular Location:
Cell membrane, Cell projection, Cytoplasmic side, Single-pass membrane protein, lamellipodium membrane

Target Information

This gene interacts with Nck and may be involved in the downstream signaling of Nck. It shares similarity with the mouse Dhm1 and the yeast dhp1 gene, which are involved in homologous recombination and RNA metabolism such as RNA synthesis and trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene; however, their full-length nature is not known.

⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.