Thermo Fisher Scientific hnRNP A1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human hnRNP A1. Validated for WB, IHC(P), and ICC/IF. Affinity-purified with >95% purity. Suitable for detecting hnRNP A1 involved in RNA binding and processing. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 51–100 of Human hnRNP A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719007 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These RNA-binding proteins associate with heterogeneous nuclear RNA (hnRNA) and are involved in pre-mRNA processing, mRNA metabolism, and transport. While primarily nuclear, some hnRNPs shuttle between the nucleus and cytoplasm. hnRNP A1 contains two quasi-RRM domains that bind RNA and is one of the most abundant core proteins of hnRNP complexes, localized mainly in the nucleoplasm. It is exported from the nucleus bound to mRNA and subsequently re-imported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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