Thermo Fisher Scientific GRE2 Polyclonal Antibody
Thermo Fisher Scientific의 GRE2 Polyclonal Antibody는 효모 GRE2 단백질을 인식하는 토끼 다클론 항체입니다. Western blot 및 ELISA에 사용 가능하며, 고순도의 친화 크로마토그래피 정제 제품입니다. PBS/glycerol 용액 형태로 제공되어 안정적 보관이 가능합니다.
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Applications
- Western Blot (WB): Assay-dependent
- ELISA: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Yeast |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Saccharomyces cerevisiae (strain ATCC 204508/S288c) GRE2 protein (1–120 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3091713 |
Target Information
GRE2 catalyzes the irreversible reduction of the cytotoxic compound methylglyoxal (MG, 2-oxopropanal) to (S)-lactaldehyde, serving as an alternative pathway to MG detoxification by glyoxalase I (GLO1). MG is produced via a glycolysis bypass from dihydroxyacetone phosphate and is implicated in cell cycle regulation and stress adaptation. GRE2 also catalyzes the reduction of 3-methylbutanal to 3-methylbutanol, functioning as a suppressor of 3-methylbutanol-induced filamentation by modulating 3-methylbutanal levels. Additionally, it plays a role in ergosterol metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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