Thermo Fisher Scientific CYP1B1 Polyclonal Antibody
CYP1B1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC 등 다양한 응용에 적합. 고순도, 액상 형태로 제공되며 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
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- PA519619
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,500 |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human CYP1B1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977864 |
Product Specific Information
Heat mediated antigen retrieval recommended prior to tissue staining.
Target Information
CYP1B1 is a 543 amino acid intracellular protein localized to the endoplasmic reticulum. It belongs to the cytochrome P450 super family of enzymes which are monooxygenases and catalyzes many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This enzyme metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17β-estradiol and is also involved in the metabolism of substances active in eye growth and differentiation, playing a putative role in ocular development. Mutated proteins are known to cause primary congenital glaucoma.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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