Thermo Fisher Scientific CYP4F11 Monoclonal Antibody (F21 P6 F5)
인간 CYP4F11 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC, ELISA에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, PBS 버퍼에 0.08% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–5 µg/mL | - |
| ELISA | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F21 P6 F5 |
| Immunogen | Synthetic peptide corresponding to human CYP450 4F11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2088406 |
Product Specific Information
A suggested positive control for this product is liposarcoma or kidney tissue.
Target Information
Cytochrome P450 proteins (CYPs) are monooxygenases that catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. CYP4F11 is an isoform of the cytochrome P450 4F protein, expressed mainly in human liver, followed by kidney, heart, and skeletal muscle.
CYP4F11 contains 524 amino acid residues sharing 80.0%, 82.3%, and 79.2% identity with CYP4F2, CYP4F3, and CYP4F8 sequences, respectively. It exhibits catalytic activity toward endogenous eicosanoids and certain clinically relevant drugs, capable of metabolizing large molecules such as erythromycin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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