Thermo Fisher Scientific WASL Monoclonal Antibody (OTI1A10), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The Wiskott-Aldrich syndrome (WAS) family of proteins are involved in transducing signals from cell surface receptors to the actin cytoskeleton. They contain multiple regulatory motifs and interact with various proteins. WASL, a homolog of WAS protein, is ubiquitously expressed with highest levels in neural tissues. It binds directly to Cdc42 and induces the formation of long actin microspikes, playing a role in actin filament organization via the Arp2/3 complex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.