Thermo Fisher Scientific TBX3 Monoclonal Antibody (OTI3B1), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

T-box 3 (TBX3) is a member of a conserved gene family sharing the T-box DNA-binding domain.
TBX3 encodes a transcriptional repressor involved in developmental regulation, including limb and mammary gland formation.
Mutations in TBX3 cause ulnar-mammary syndrome (MIM 181450), affecting limb, gland, tooth, hair, and genital development.
TBX3 is also implicated in tumor progression and osteoblast differentiation.
Overexpression of TBX3 can lead to cell immortalization in vitro, and truncated forms are found in plasma samples.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.