Thermo Fisher Scientific SPDYA Polyclonal Antibody
SPDYA 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 응용(ELISA, WB, IHC, ICC)에 최적화된 고순도 항체. Protein A로 정제되었으며, 세포주기 조절 연구에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SPDYA (amino acids 98–180) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Speedy A (SPDYA), also known as SPDY1, Ringo3, or SPY1, is a 313-amino-acid nuclear protein belonging to the speedy/ringo family.
It is highly expressed in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver, spleen, and placenta.
Speedy A regulates the G1/S phase transition by binding and activating Cdc2 p34, Cdk2, and p27, and mediates cell survival during DNA damage.
Multiple isoforms exist due to alternative splicing. The SPDYA gene is located on human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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