Thermo Fisher Scientific MNAT1 Polyclonal Antibody
MNAT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat에 반응하며, Protein A로 정제된 1 mg/mL 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human MNAT1 (amino acids 51–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Progression through the cell cycle requires activation of cyclin-dependent kinases (Cdks). The monomeric catalytic subunit Cdk2, essential for cell cycle initiation, is inactive until bound by regulatory cyclins such as cyclin D1 and phosphorylated at Thr 160. The enzyme responsible for this phosphorylation, Cdk-activating kinase (CAK), includes a catalytic subunit, a regulatory subunit, and a subunit of unknown function. The regulatory subunit, cyclin H, is required for activation of Cdk7. Mat1, a protein associated with the cyclin H–Cdk7 nuclear complex, is essential for forming an active Cdk–cyclin complex and displays kinase activity toward both Cdk activation domains and the C-terminal domain of RNA polymerase II.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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