Thermo Fisher Scientific PRDX5 Monoclonal Antibody (4C3)
PRDX5 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단일클론 항체(4C3)로, WB, ELISA, IP에 사용 가능. 인간 재조합 단백질을 면역원으로 하며 비결합형 액상 형태. 연구용으로 세포 내 산화 스트레스 관련 단백질 분석에 적합.
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Thermo Fisher Scientific PRDX5 Monoclonal Antibody (4C3)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C3 |
| Immunogen | Purified, recombinant human fragment protein (without mitochondrial leader sequence) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1086603 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family whose mammalian members are associated with cell proliferation, differentiation, and apoptosis.
Mammalian Prx includes six members categorized as typical 2-Cys, atypical 2-Cys, and 1-Cys Prx.
Except for Prx VI (1-Cys subgroup), the other five 2-Cys Prx isotypes exhibit thioredoxin-dependent peroxidase (TPx) activity using thioredoxin, thioredoxin reductase, and NADPH as a reducing system.
Mammalian Prxs are 20–30 kDa in size and show varied subcellular localization:
- Prx I, II, and VI: cytosol
- Prx III: mitochondria
- Prx IV: endoplasmic reticulum and secretion
- Prx V: peroxisome, mitochondria, and cytosol
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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