Thermo Fisher Scientific RAE1 Polyclonal Antibody
RAE1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 검증 완료. C-말단 합성 펩타이드로부터 생산되었으며, Human에 반응. 액상 형태로 제공되며, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–8 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human RAE1 (aa 312–361) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608271 |
Product Specific Information
- Peptide sequence: EQLDQPISAC CFNHNGNIFA YASSYDWSKG HEFYNPQKKN YIFLRNAAEE
- Sequence homology:
Cow: 100% / Dog: 100% / Guinea Pig: 100% / Horse: 100% / Human: 100% / Mouse: 100% / Rabbit: 100% / Rat: 100% / Zebrafish: 93%
Target Information
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes lead to accumulation of poly-containing mRNA in the nucleus, suggesting involvement in RNA export. The human RAE1 protein, a homolog of yeast Rae1, contains four WD40 motifs and localizes to nucleoplasmic foci, the nuclear rim, and cytoplasmic meshwork-like structures. It is implicated in nucleocytoplasmic transport and attachment of cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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