Thermo Fisher Scientific RAE1 Polyclonal Antibody
RAE1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 적용 가능. 고순도 Affinity Chromatography 정제. 인체 및 다양한 종에 반응. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–8 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human RAE1 (aa 319–368) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608272 |
Product Specific Information
- Peptide Sequence: SACCFNHNGN IFAYASSYDW SKGHEFYNPQ KKNYIFLRNA AEELKPRNKK
- Sequence Homology: Cow 100%; Dog 100%; Guinea Pig 100%; Horse 100%; Human 100%; Mouse 100%; Rabbit 100%; Rat 100%; Zebrafish 100%
Target Information
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes result in accumulation of poly-containing mRNA in the nucleus, suggesting involvement in RNA export. The human RAE1 protein is a homolog of yeast Rae1, containing four WD40 motifs, and localizes to distinct foci in the nucleoplasm, nuclear rim, and cytoplasmic meshwork structures. It is implicated in nucleocytoplasmic transport and attachment of cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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